Concept
Gene Ontology
Overview
The Gene Ontology (GO) is a major bioinformatics initiative to unify the representation of gene and gene product attributes across all species. More specifically, the project aims to: 1) maintain and develop its controlled vocabulary of gene and gene product attributes; 2) annotate genes and gene products, and assimilate and disseminate annotation data; and 3) provide tools for easy access to all aspects of the data provided by the project, and to enable functional interpretation of experimental data using the GO, for example via enrichment analysis. GO is part of a larger classification effort, the Open Biomedical Ontologies, being one of the Initial Candidate Members of the OBO Foundry.
Whereas gene nomenclature focuses on gene and gene products, the Gene Ontology focuses on the function of the genes and gene products. The GO also extends the effort by using a markup language to make the data (not only of the genes and their products but also of curated attributes) machine readable, and to do so in a way that is unified across all species (whereas gene nomenclature conventions vary by biological taxon).
Overview adapted from Wikipedia (CC BY-SA 4.0; see the article history for authors).
Possible passages
Found by search and not yet checked by a person; they may only mention the idea in passing.
Now, we propose in the first place to show, that this law of organic progress is the law of all progress. Whether it be in the development of the Earth, in the development of Life upon its surface, in the development of Society, of Government, of Manufactures, of Commerce, of Language, Literature, Science, Art, this same evolution of the simple into the complex, through successive differentiations, holds throughout…
Herbert Spencer, Essays on education and kindred subjects
States what Gene Ontology is.
The more or less spherical germ from which every organism, animal and vegetal, proceeds, is comparatively general: alike in the sense that in appearance and chemical nature it is very similar to all other germs; and also in the sense that its form is less markedly distinguished from the average forms of objects at large, than is that of the mature organism—a contrast which equally holds of internal structure. But…
Herbert Spencer, First Principles
Close in meaning to Gene Ontology; the term itself is not named.
Thus, the notion of correlation is first used in current science as it might be used by an advocate of finality; it is understood that this is only a convenient way of expressing oneself, that one will correct it and fall back on pure mechanism when explaining the nature of the principles and turning from science to philosophy. And one does then come back to pure mechanism, but only by giving a new meaning to the…
Henri Bergson, Creative Evolution
States what Gene Ontology is.
Related ideas
Opposing perspectives
Place in the tradition
Part of Ontology.