Concept
Jaundice
Overview
Jaundice, also known as icterus, is a yellowish or, less frequently, greenish pigmentation of the skin and sclera due to high bilirubin levels. Jaundice in adults typically indicates the presence of underlying diseases involving abnormal heme metabolism, liver dysfunction, or biliary-tract obstruction. The prevalence of jaundice in adults is rare, while jaundice in babies is common, with an estimated 80% affected during their first week of life. The most commonly associated symptoms of jaundice are itchiness, pale feces, and dark urine.
Normal levels of bilirubin in blood are below 1.0 mg/dl (17 μmol/L), while levels over 2–3 mg/dl (34–51 μmol/L) typically result in jaundice. High blood bilirubin is divided into two types: unconjugated and conjugated bilirubin.
Causes of jaundice vary from relatively benign to potentially fatal. High unconjugated bilirubin may be due to excess red blood cell breakdown, large bruises, genetic conditions such as Gilbert's syndrome, not eating for a prolonged period of time, newborn jaundice, or thyroid problems. High conjugated bilirubin may be due to liver diseases such as cirrhosis or hepatitis, infections, medications, or blockage of the bile duct, due to factors including gallstones, cancer, or pancreatitis. Other conditions can also cause yellowish skin, but are not jaundice, including carotenemia, which can develop from eating large amounts of foods containing carotene—or medications such as rifampin.
Treatment of jaundice is typically determined by the underlying cause. If a bile duct blockage is present, surgery is typically required; otherwise, management is medical. Medical management may involve treating infectious causes and stopping medication that could be contributing to the jaundice. Jaundice in newborns may be treated with phototherapy or exchanged transfusion depending on age and prematurity when the bilirubin is greater than 4–21 mg/dl (68–365 μmol/L). The itchiness may be helped by draining the gallbladder, ursodeoxycholic acid, or opioid antagonists such as naltrexone. The word jaundice is from the French jaunisse, meaning 'yellow disease'.
Overview adapted from Wikipedia (CC BY-SA 4.0; see the article history for authors).
Possible passages
Found by search and not yet checked by a person; they may only mention the idea in passing.
To all which phenomena some physician or philosopher who was able to see the one in many has given the name of bile. The various kinds of bile have names answering to their colours. Lymph or serum is of two kinds: first, the whey of blood, which is gentle; secondly, the secretion of dark and bitter bile, which, when mingled under the influence of heat with salt, is malignant and is called acid phlegm.
Plato, Timaeus
States what Jaundice is.
But all else that may be called kinds of bile, receive, according to colour, a name peculiar to each. As for _lymph_ (ἴχωρ), the whey of the blood, it is gentle and mild: while the sediment of black, acid bile, is fierce and wild;—and when mingled by heat with anything of a saline quality, it is called _acid phlegm_. Again, the moisture running from new and tender flesh mingled with the air, which is afterwards…
Plato, The works of Plato
States what Jaundice is.
For neither by touching or hearing the voice of their beloved are they so much wounded and wrought upon, as by looking and being looked upon again. There is such a communication, such a flame raised by one glance, that those must be altogether unacquainted with love that wonder at the Median naphtha, that takes fire at a distance from the flame. For the glances of a fair one, though at a great distance, quickly…
Plutarch, Complete Works of Plutarch — Volume 3
Names Jaundice twice.
Philosophers who discussed Jaundice
Related ideas
Place in the tradition
Part of Analytic philosophy.