Concept
Substance dependence
Overview
Substance dependence, also known as drug dependence, is a biopsychological situation whereby an individual's functionality is dependent on the necessitated re-consumption of a psychoactive substance because of an adaptive state that has developed within the individual from psychoactive substance consumption that results in the experience of withdrawal and that necessitates the re-consumption of the drug. A drug addiction, a distinct concept from substance dependence, is defined as compulsive, out-of-control drug use, despite negative consequences. An addictive drug is a drug which is both rewarding and reinforcing. ΔFosB, a gene transcription factor, is now known to be a critical component and common factor in the development of virtually all forms of behavioral and drug addictions, but not dependence.
The International Classification of Diseases classifies substance dependence as a mental and behavioural disorder. In the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) (released in 2013), substance abuse and substance dependence were eliminated and replaced with the single diagnosis of substance use disorders. This was done because "the tolerance and withdrawal that previously defined dependence are actually very normal responses to prescribed medications that affect the central nervous system and do not necessarily indicate the presence of an addiction."
Overview adapted from Wikipedia (CC BY-SA 4.0; see the article history for authors).
Possible passages
Found by search and not yet checked by a person; they may only mention the idea in passing.
They are always real, because they concern the existence of substance (negations are only determinations, which express the non-existence of something in the substance). Now, if to this real in the substance we ascribe a particular existence (for example, to motion as an accident of matter), this existence is called inherence, in contradistinction to the existence of substance, which we call subsistence. But hence…
Immanuel Kant, The Critique of Pure Reason
States what Substance dependence is.
This process is called "sublimation," and in adopting this process we subscribe to the general standard which places social aims above selfish sexual desires. Sublimation is, as a matter of fact, only a special case of the relation of sexual to non-sexual desires. We shall have occasion to talk more about this later in another connection.
Sigmund Freud, A General Introduction to Psychoanalysis
States what Substance dependence is.
Assumptions of this kind about the nature of sexual desire have found acceptance in the mind of the people since the beginning of time; love is called an “intoxication,” it can be induced by “potions”—in these ideas the agency at work is to some extent projected on to the outer world. We find occasion at this point to remember the erotogenic zones, and to reflect upon the proposition that sexual excitation may arise…
Sigmund Freud, Introductory lectures on psycho-analysis
States what Substance dependence is.
Related ideas
- Substance abuse
- Mental disorder
- Psychology
- Dopamine
- Ivan Pavlov
- Phenomenon
- Agriculture
- Reward system
- Applied behavior analysis
Place in the tradition
Part of Free will.